Recent Publications: Molecular Orthopaedics Lab

Mesenchymal-specific knockout of ESET histone methyltransferase causes ectopic hypertrophy and terminal differentiation of articular chondrocytes. Lawson KA, Teteak CJ, Zou J, Hacquebord J, Ghatan A, Zielinska-Kwiatkowska A, Fernandes RJ, Chansky HA, Yang L. J Biol Chem. 2013 Sep 20. [Epub ahead of print] PMID: 24056368

ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates. Yang L, Lawson KA, Teteak CJ, Zou J, Hacquebord J, Patterson D, Ghatan AC, Mei Q, Zielinska-Kwiatkowska A, Bain SD, Fernandes RJ, Chansky HA. Dev Biol. 2013 May 4. doi:pii: S0012-1606(13)00225-X. 10.1016/j.ydbio.2013.04.031. [Epub ahead of print] PMID: 23652029

FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells. Yang L, Hu HM, Zielinska-Kwiatkowska A, Chansky HA. Biochem Biophys Res Commun. 2010 Nov 5;402(1):129-34. doi: 10.1016/j.bbrc.2010.09.129. Epub 2010 Oct 8. PMID: 20933505

Proper expression of helix-loop-helix protein Id2 is important to chondrogenic differentiation of ATDC5 cells. Yang L, Ma X, Lyone A, Zou J, Blackburn ML, Pan J, Yang D, Matsushita H, Mei B, Zielinska-Kwiatkowska A, Chansky HA. Biochem J. 2009 May 1;419(3):635-43. doi: 10.1042/BJ20081715. PMID: 19175360