Spine Surgery for Rheumatoid Arthritis.

Edited By: Jens R. Chapman, M.D.
Last updated Wednesday, December 29, 2004

Review of the condition

Characteristics of rheumatoid arthritis of the spine

As with any joint in the body, the small joints of the spine can be destroyed by rheumatoid arthritis. This can lead to instability, pain and in advanced cases to compression of the spinal cord and nerve roots emerging from it. This occurs most commonly in the upper neck, but may affect the lower neck or lower back as well.

Incidence and risk factors

One in five to one in three patients with RA have spinal involvement.

Diagnosis

Aside from a physical examination, which includes assessment of the patient’s neurologic function, radiographs (X-rays) are obtained. These usually include neck X-rays in which the patient is first asked to bend their head forward, then backward. Obviously, if the patient has symptoms in other areas of the spine, X-rays of other areas of the spine may have to be obtained as well. If these X-rays show reason for concern an MRI scan will usually be ordered next. Sometimes, a CAT scan (CT) or Bone-scan may be added.

Medications

In early stages of RA, anti-inflammatory medications can be effective in decreasing pain and may slow the progression of joint destruction caused by RA.

Exercises

Once joint destruction of the spine has set in, there are no specific exercises that can stop or arrest the development of spinal instability. Maintenance of a normal body posture and a low-impact exercise program are necessary to avoid severe secondary problems, such as spontaneous spine fractures and maintain reasonable levels of cardiopulmonary fitness. Chiropractic manipulation of RA patients with spinal involvement is, however, clearly contraindicated due to the risk of causing spinal instability to worsen. Cases of paralysis after spine manipulation have been reported.

Possible benefits of spine surgery for rheumatoid arthritis

Spine surgery can improve the quality of life of an affected RA patient in several major ways:

  • By resecting a diseased joint and creating a permanent bond between the affected vertebrae (in a procedure referred to as "fusion"), rheumatoid arthritis and its related symptoms are extinguished from that area.
  • Restoration of a normal spinal alignment prevents deterioration of basic vital functions, such as cardiopulmonary fitness.
  • Stabilization and, if necessary, realignment of the spine can protect the patient’s spinal cord from potentially catastrophic injury.
  • Decompression of compromised nerves can decrease pain, halt progressive loss of nerve function and may even lead to improved function.

Who should consider spine surgery for rheumatoid arthritis?

RA patients who have unrelenting pain, experience loss of neurologic function, such as dexterity in hands and feet, or have progressive loss of spine stability as shown on X-rays should consider such surgery.

What happens without surgery?

The best case scenario includes ocasional neck and back pain necessitating anti-inflammatory medication use and soft neck collar with the patient maintaining an active life-style.

A worst case scenario might be sudden death through acute spinal cord compression in an area right below the skull.

Surgical options

Stabilization of the spine may be necessary in areas where the arthritis has led to unacceptable pain and instability. Such a procedure ("fusion") is nowadays carried out with resection of the involved joint, placement of a small bone graft taken from the pelvis into the former joint and stabilization with small titanium screws, rods and plates.

Effectiveness

Once a solid fusion is obtained, the results are permanent. Eighty-five per cent of RA patients with fusions report good or excellent relief of their preoperative symptoms.

Urgency

Should a spinal cord or nerve compression be manifest, surgical care should be considered with urgency (within weeks). In absence of neurologic concerns, a patient with RA can be followed serially with X-rays and examinations on an annual or semi-annual basis.

Risks

The most common risks of spine surgery in RA historically were surgical wound infections and failure of the spinal hardware to provide adequate stability to the spine. With the advent of modern spinal instrumentation systems and improved understanding of medical care needs of RA patients, these occurrences have dramatically decreased.

One in ten patients with a spine fusion performed ten years or more ago may experience increased pain in their spine due to instability at a level below a fusion. If this is noticed the previous fusion may have to be extended to include the newly affected levels.

Managing risk

Surgical wound infections or hardware failures may require repeat surgery. Infections will also require intravenous antibiotics given for several weeks.

Costs

For the University of Washington systems please contact the Spine Care patient coordinators:

  • Diane Maguire: (206) 598-4290
  • Sue Stone: (206) 731-2331

Surgical team

Spine surgery in a patient with RA requires an experienced, fellowship trained spine surgeon, either from an Orthopaedic Surgery or Neurological Surgery background. The resources of a large hospital with immediate access to multiple specialties and an in-house MRI scan are important due to the potential complexities of care that patients with RA may encounter.

Finding an experienced surgeon

Contact:

  • MEDCON (206) 543-5300
  • American Academy of Orthopaedic Surgeons: 1 800 346 AAOS
  • Washington State Medical Society: (206) 441-9762. Will connect to local County Medical Society.

Facilities

A large hospital, usually with academic affiliation and equipped with state of the art radiologic imaging equipment and Intensive Medicine Care Unit, is clearly preferable in the care of patients with spinal RA.

Technical details

The surgeon will expose the affected area of the spine through an incision in the back or occasionally in the front of the neck. Using a high-speed dental-type drill the diseased joints of the spine are then resected. A small bone graft is removed from the patient’s pelvis through a separate incision. Occasionally, bone graft substitutes derived from non-organic sources can be used instead. Under digital fluoroscopy (a form of "live" X-rays) precision drill holes are then placed into specific bony sections of the spine. These are then filled with small titanium screws and connected with rods or plates. Occasionally a supplemental cable is placed between adjacent bone segments to secure a bone graft. Should the spinal cord or nerves need to be decompressed, this is then usually performed under a microscope with specialized microscopic instruments. A meticulous skin closure is then performed to ensure rapid wound healing. Usually, a patient can then be mobilized within a day from surgery using a neck collar. Occasionally, patients with very poor bone stock (such as osteoporosis) may require immobilization with a Halo and vest (a graphite ring placed around the head and secured with posts to a body vest).

Anesthetic

A general anesthetic is essential for this type of surgery.

Length of spine surgery for rheumatoid arthritis

Depending upon the number of levels to be fused and complexities of decompression of neurologic structures, surgery takes between 2 and 8 hours.

Pain and pain management

Typically, the first two days after surgery can be quite painful to patients with spine fusion surgery. Therefore patients are usually given intravenous patient controlled analgesia machines. These programmable machines supply pain medication to a patient automatically, yet allow the patient to add further doses if needed within safe limits. After the first 2 days patients usually require oral pain medication for 2 to 12 weeks.

Hospital stay

Patients with complex spine surgery or multiple medical problems usually are observed in an Intensive Care Unit for 1-2 days. A hospital stay of 3-7 days is usually necessary.

Recovery and rehabilitation in the hospital

Patients are usually mobilized into an upright position or even out of the bed towards the end of the Intensive Care Unit stay. Patients are returned to most regular activities of daily living within 3 – 5 days.

Hospital discharge

Spine fusion patients are usually asked to wear a supportive and protective neck brace for 2-3 months after surgery. These braces should usually be worn around the clock. We strongly recommend an early return to a light aerobic conditioning program.

Convalescent assistance

We recommend help with showering, domestic maintenance, such as cooking and utilization of a driver for a minimum of 3 weeks, sometimes more.

Surgery for Rheumatoid arthritis of the spine at the University of Washington

If you are interested in making an appointment to discuss this procedure, you can request an appointment using our online referrals website. To request a referral online, please click here. You can also call 206-598-6293 to make an appointment.