Continuing Medical Education: Understanding Osteoarthritis.
Edited By: Gregory C. Gardner, M.D.
Last updated Friday, January 07, 2005
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Conclusion & bibliographyConclusion As a resident in internal medicine, I was taught to treat OA with
NSAIDs and if this did not help, with a referral to an orthopedist or
rheumatologist. In this lecture, I have tried to point out the variety
of therapeutic options available to every physician who takes care of
patients with OA. The treatment of OA is a "program" in which the
physician and patient each have their responsibilities with the goal of
improving the quality of life for the patient with OA.
References - Brandt KD. Osteoarthritis. Clin Geriatr Med 1988;4:279-293.
The most important theories concerning the pathogenesis of osteoarthritis.
- Davis MA. Epidemiology of osteoarthritis. Clin Geriatr Med 1988;4:241-255.
Risk factors for and the natural history of osteoarthritis.
- Hammerman D. The biology of osteoarthritis. N Engl J Med 1989;320:1322-1330.
Biology of normal articular cartilage and the changes that occur with osteoarthritis.
- Furst DE, Paulus HE. Aspirin and other nonsteroidal
antiinflammatory drugs. In McCarty D, Ed. Arthritis and Allied
Conditions. 12th Edition, Lea & Febiger, Philadelphia,1993, pp.
507-543.
Outlines the mechanism of action of NSAIDs and discusses each NSAID individually, detailing their reported adverse reactions.
- Bradley JD, Brandt KD, Katz BP, Kalasinski LA. Comparison of an
intiinflammatory dose of ibuprofen, an anlagesic dose of ibuprofen, and
acetaminophen in the treatment of patients with osteoarthritis of the
knee. N-Engl- Med 1991;325:87-91.
Controlled trial of ibuprofen in 2 doses compared to acetaminophen
for knee osteoarthritis with no difference of significance noted
although several trends favored the ibuprofen. The authors suggest that
acetaminophen is more appropriate therapy in most patients with
osteoarthritis due to its favorable safety profile.
- McCarthy GM, McCarty DJ. Effect of topical capsaicin in the therapy
of painful osteoarthritis of the hands. J Rheumatol 1992;19:604-607
Controlled trial of capsaicin cream in osteoarthritis of the hand. Discussed in the text.
Surgery for arthritis at the University of Washington, Department of Orthopaedics and Sports Medicine, Seattle, Washington If you are interested in making an appointment to discuss this procedure in Seattle, you can request an appointment using our online referrals website. To request a referral online, please click here. You can also call 206-598-4288 to make an appointment. Our clinical center is located in Seattle Washington, USADisclaimer
This resource has been provided by the University of Washington Department of Orthopaedics and Sports Medicine as general information only. This information may not apply to a specific patient. Additional information may be found at http://www.orthop.washington.edu or by contacting the UW Department of Orthopaedics and Sports Medicine.
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