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HomeAboutBasics of diabetes basicsImmediate medical attentionFacts and myths Prognosis and impactsIncidence and risk factorsSymptomsCauses and effectsDiagnosis and evaluation Management and treatment CopingResearchConclusion

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Diabetes Basics.

Last updated Thursday, February 10, 2005

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Basics of diabetes basics

Diabetes is a condition caused by lack of a chemical in the body (a hormone) called insulin. There are two major forms of diabetes. In type 1 diabetes, eventually no insulin is produced and individuals require insulin injections for survival. It used to be thought this only presented in children but it is now clear this can occur at any age.

The other, more common form of diabetes, called type 2 diabetes, occurs due to the body's resistance to the effects of insulin in addition to an insufficient quantity of insulin. However, in this type of diabetes there is usually some insulin produced.

For both types of diabetes blood glucose levels are elevated. Furthermore, people with diabetes are prone to certain complications not seen in those without diabetes. These complications involve the eye (retinopathy), kidney (nephropathy), and nerves (neuropathy). People with diabetes also get early hardening of the arteries (atherosclerosis), leading to early heart attacks and strokes. The good news for people with diabetes is that with proper care, all of these problems can be avoided.

Immediate medical attention

Uncontrolled diabetes presents with frequent thirst and urination. Over time patients will become dehydrated as the glucose is "spilling" over into the urine. If insulin deficiency is severe enough, fat stores are used for energy as glucose cannot get into cells. This problem is much more common with type 1 diabetes and is called "ketoacidosis". It can be diagnosed at home with a simple urine test. When significant ketones are found in the urine it is important to be in touch with a physician immediately.

There are other conditions that require immediate attention. Blurry vision in someone with known diabetic eye disease or someone with a long history of diabetes may mean there was bleeding in the back of the eye. This may require treatment by an eye doctor. An infection on the bottom of the foot is a common problem that needs immediate attention too. When people with long-standing diabetes experience heart disease, they often do not get the typical chest pain (angina) that occurs in those people without diabetes. Often their symptoms of heart disease presents with shortness of breath with minimal exertion. This should also prompt a call to a physician.

Swelling (edema) of the ankles is another common symptom that may be a sign of a serious problem. For example, new swelling in the ankles may suggest that large quantities of protein are being lost in the urine--the first problem noted with kidney disease. Swelling may also be seen with early heart failure, a common problem in people with diabetes. Alternatively, swelling may be due to a non-serious condition, such as a side effect of a new medication or even a clue that the veins which take blood back to the heart are not working as well as they could be. Therefore, anytime new swelling is noted it should be reported to your physician.

Facts and myths

Diabetes does not "skip" generations. However, we don't understand the exact reasons why some people get diabetes and others don't.

A common misconception is that if children eat too much candy they will "catch" diabetes. Although we are seeing more type 2 diabetes in young people, this misconception refers to type 1 diabetes and is not true.

For people with diabetes, many feel that occasional blood glucose levels over 200 mg/dL will have long-term consequences. This is not true at all as it is common for glucose levels to rise above this level in almost everyone with diabetes.

There are also many misconceptions regarding food. One common one is that fresh fruit is "healthy" because it is "natural". While this may be true, fruit is also very effective at causing the blood glucose to rise quickly. Fruit juices are the most common problem here. Many people also don't realize how much milk causes blood glucose to rise. Finally, there are many misunderstandings regarding the glucose effects of alcohol. Depending on the type of alcohol consumed and the amount of food consumed, blood glucose can actually go DOWN when drinking so this needs to be done with caution.

There is also a common misunderstanding about exercise. While it is true that exercise usually results in lower blood glucose levels, if a person with type 1 diabetes exercises without sufficient insulin in the bloodstream (for example, more than 12 hours after the last shot of NPH insulin) the blood glucose can actually go UP! In fact exercise at this time period can actually lead to ketoacidosis. Therefore, for people with type 1 diabetes great attention is required balancing blood glucose levels and exercise. Since high blood glucose often occurs when insulin levels in the blood are low, the usual recommendation is to wait until the blood sugar is below 250 mg/dL before participating in strenuous exercise.


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