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Polymyalgia Rheumatica.

Last updated Thursday, February 10, 2005

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Management and treatment

How is polymyalgia rheumatica treated?

Treatment includes medications to help reduce inflammation as well as proper exercise and rest for some people in order to maintain joint flexibility, muscle strength, and function.

The goal in treating PMR is to help relieve pain, stiffness, and achiness.

What medications are used to treat or manage polymyalgia rheumatica?

Corticosteroid drugs, strong medications that help reduce inflammation, are the usual medications used to treat PMR. They also help relieve stiffness and achiness. They act quickly in PMR. Most people feel better within a few days or sometimes even the next day. There are many forms of corticosteroids. For example, prednisone is a medication often used in PMR.

If your doctor places you on a corticosteroid, you should follow instructions carefully. Your doctor may have you take the entire dose in the morning or have you divide the dose throughout the day. You probably will feel better very soon after starting this medicine. It is important to keep taking the medicine even though you are feeling better. PMR can return if you stop this medicine too quickly. The usual dose of prednisone is between 10 and 20 mg per day.

You may need to take corticosteroids as briefly as six months or as long as one or two years. Some people may need to be treated even longer. As you improve while on this medicine, it is likely that the dose will slowly be decreased. Follow your doctor's instructions on how often to take your medication. Do not try to cut back the dose on your own or suddenly stop taking your medication, since your symptoms can worsen.

Potential side effects of corticosteroids

Over a long period, corticosteroids may cause such side effects as:

  • weight gain
  • thinning of the bones (osteoporosis)
  • depression and mood swings
  • increased risk of infection
  • cataracts
  • glaucoma
  • worsening of diabetes or new diabetes in someone who has never had it
  • thinning of the skin and easy bruising
  • rounding of the face
  • difficulty sleeping
  • high blood pressure (hypertension)
  • avascular necrosis, an arthritis like condition that most commonly affects the hips or shoulders, and can be treated with total hip replacement or total shoulder replacement

These medications affect everyone differently. You may have some of these side effects or none at all. If they do occur, most of these side effects will go away when the medication is stopped or decreased. Your doctor can give you some helpful tips about diet and exercise to help with some of the side effects. If you are placed on this medication, it is because your doctor feels that your symptoms are serious enough to need this medication. Let your doctor know about any side effects that you may be experiencing.

You'll need to see your doctor regularly once you start taking medication. Tell your doctor how the medicine has affected your symptoms. Report any side effects that you may have developed, such as weight gain or depression. Your doctor may use various tests like the ESR to adjust your medication. Even though you may feel well, it is important to see your doctor regularly so you can be checked for any signs of a relapse. Once you have responded to corticosteroids, the goal is to slowly reduce the dose to the lowest level necessary to control symptoms and prevent a relapse.

Special instructions for corticosteroids

Corticosteroids are different from many of the medications you may have taken in the past. Your body naturally produces small amounts of hormones that are forms of corticosteroids. When you take corticosteroids for more than a few days, your body may stop producing some of these hormones. This is not permanent. Your body gradually will start making the hormones again as the dose of your medication is lowered.

Your body depends on corticosteroids for many daily functions. These hormones are important during times of stress. Your body does not care whether it receives corticosteroids from natural hormones or from medication. However, if you suddenly stop taking this medication, your body may not make enough hormones on its own right away. This can make you seriously ill. Also, your body's need for this medicine is greatest in the morning. That is one reason why most people should take some or all of the medicine in the morning.

Some important rules about corticosteroids are as follows:

  • Do not stop this medication without discussing it with your doctor.
  • Do not try to decrease this medication on your own. You and your doctor will need to work together to gradually wean you off of this medicine.
  • Tell your other doctors and other health professionals that you are taking this medicine. In some cases, they may want to delay certain types of treatments if you are taking corticosteroids. Your medication may need to be increased for short periods of time if your body is under a lot of stress--for example, if you are recovering from surgery or a serious illness. Even after you have been off corticosteroids for as long as one year, you should tell your doctor that you used to take them.
  • Wear medical identification to let people know that you take these medications in case a medical emergency occurs. Should you be involved in an accident or become seriously ill, it is very important that this information be known. Also, tell your family that you are taking corticosteroids so they can tell others in an emergency.
  • If you become ill and are unable to take this medication because of vomiting, let your doctor know right away. You may need to increase your usual dose for several days when you are sick.

Many of the side effects of corticosteroids are directly related to the dose given. The therapeutic goal is to always find the lowest effective dose that will avoid as many of the side effects as possible. You probably will not need large doses of corticosteroids unless your PMR is accompanied by giant cell arteritis. Serious side effects are much less common with the low doses of corticosteroids usually used in PMR, but it still is wise to follow these safety rules.


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