Paget's Disease.

Diagnosis and evaluation

Diagnosis

Diagnostic tests

Diagnosis of Paget's disease can be made by X-rays of the affected bones. A bone scan often helps to determine the location and extent of bone involvement.

Blood tests may be run to determine the presence of increased amounts of alkaline phosphatase (a product of bone forming cells). Urine tests (such as a 24-hour urine collection) may be run to determine the presence of an increased amount of hydroxyproline (another product of bone breakdown). A bone biopsy is rarely needed to ensure the accuracy of the diagnosis.

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