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When Cancer Spreads to the Bone: Surgery for Metastatic Bone Disease

Last updated Thursday, December 13, 2007

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Prognosis and impacts

How serious is metastatic bone disease? Is metastatic bone disease chronic?

The appearance of metastatic bone disease is very serious and can worsen a patient’s overall prognosis. Left untreated, it has a severe effect on the remaining quality of life. A patient can become profoundly hypercalcemic (have very high levels of calcium in the blood), which can be dangerous. When too much calcium is released into the bloodstream, the patient can become prone to gastrointestinal symptoms, psychiatric symptoms such as delusions, and kidney stones. If the cancer spreads from the bones to the lungs, the consequences can be fatal. In a few patients whose initial treatment was successful, metastatic bone disease can be a chronic problem. The patient may, for example, have an isolated problem in a leg bone, get it treated, and live several years before the disease reappears in the spine or arm.

Is metastatic bone disease deadly?

How lethal metastatic bone disease is depends on the patient’s original type of cancer and how much the cancer has spread. Widespread metastatic bone disease has a poor prognosis. However, the outlook may be better for those patients who have just one or two spots in their bones. Patients may find some peace of mind from knowing that not all patients with metastatic bone disease have a grim future. Medication and surgery can help keep the symptoms of the disease at bay and help permit a good level of activity.

Will metastatic bone disease cause pain?

Pain is usually what prompts the patient to seek medical attention. Rarely is metastatic bone disease an incidental finding during a routine exam. Patients usually describe the pain as body aches that occur during the night, and feel like a bad toothache.

Will metastatic bone disease be debilitating?

How debilitating metastatic bone disease is varies from person to person, depending on which part of the skeleton is affected. For example, a metastasis that appears in the right arm of a left-handed person causes less trouble than if the patient were right handed.

Will metastatic bone disease cause discomfort?

Metastatic bone disease will cause some degree of discomfort. The amount will vary from person to person. Radiation treatment, medications, surgery, and other pain management techniques can often make the patient more comfortable. Patients should let their doctors and nurses know if they are in pain, where it hurts, how severe it is, and how the pain is affecting their daily lives. Their doctors and nurses can then find ways to try to reduce the pain. More can be done today to lower the musculoskeletal pain from cancer than was available in the past.

Is metastatic bone disease curable?

While treatment may improve the patient’s comfort and function, reduce pain, and prevent additional suffering from fractures, treatment is rarely curative.

Will metastatic bone disease change the patient?s ability to have children or get pregnant?

Metastatic bone disease has no effect on fertility. However, because metastatic bone disease usually doesn’t occur until after age 40, most women who develop metastatic bone disease are no longer in their prime childbearing years.

Will metastatic bone disease change the patient's independence?

Metastatic bone disease may lessen independence in a significant number of, but not all, patients. Some patients with metastatic bone disease have chronic pain that requires treatment with sedating medications. Those whose bones are affected in the lower part of the body may have difficulty walking. If the bones in the arms are affected, patients may have problems carrying out the daily activities of living, such as cooking, writing, cleaning, shopping, and personal care. Patients will likely have to stop working. Some will need to use a wheelchair to get around. Because of their restricted range of movement, and if they are taking narcotics to curb their pain, some patients will not be able to drive.
 
 
The loss of independence may be especially difficult for cancer patients who felt they have gotten their daily life back and have been disease-free from cancer for 10 or 20 years, only to have their activities curtailed by pain and bone deterioration. However, surgery or radiation might be able to reduce the pain to the point where narcotics are not needed, and might be able to reduce other disabilities from the disease.

Will metastatic bone disease change the patient's ability to move about?

The limitations that metastatic bone disease places on mobility depends on which bones have the disease, how many bones are involved, and how much area of each bone is damaged, and the severity of the damage. Patients should check with their doctor to see if treatment can help restore some of their lost mobility or reduce their risk of fractures.

Will metastatic bone disease alter activities of daily living (e.g. work, sports, housework, etc.)?

Whether metastatic bone disease alters activities of daily living depends on where in the skeleton the disease is occurring. For example, metastasis in the arm bones or in the upper backbone may limit the ability to do housework, work at a computer, use hand tools, or do lifting. In addition, a patient’s energy for accomplishing tasks may be low, especially while he or she is receiving radiation.

Will metastatic bone disease cause fatigue or changes in metabolism?

As with many other forms of cancer, metastatic bone disease is often accompanied by fatigue. In addition, the narcotics to treat pain are often sedating. Radiation and chemotherapy can also cause fatigue, and patients often suffer from sleep problems, including being woken up by pain. This loss of nighttime sleep can lead to daytime drowsiness. Depression may also make it hard to get up the energy to do things. Some forms of cancer can cause anemia and its resulting tiredness. Some causes of fatigue, such as depression, anxiety, insomnia, and anemia, can be addressed to reduce its impact.

Will metastatic bone disease require a change in diet?

There are no specific diets, dietary restrictions, or requirements for people who have metastatic bone disease.

Will metastatic bone disease have implications for relationships, social support, and interactions with family?

A person who has metastatic bone disease may need more practical help, because the disease might have significant impact on his or her independence and mobility. A patient will likely have repeated visits to the doctor, which will take up a sizeable amount of time, especially if the patient lives in a rural town and must travel a long distance for treatment. Sometimes receiving cancer treatment, or caring for a relative with metastatic bone disease, can seem burdensome at times. For example, radiation therapy often requires several weeks of daily treatments at the hospital or clinic. If the patient already has stresses in his or her life, or has had difficult interpersonal relationships before the disease occurred, these may become worse because of the demands of living with cancer. On the other hand, sometimes the appearance of a serious disease can change people’s outlooks in such a way that family, friendships, and other personal relationships become more important and stronger.

What other impacts might metastatic bone disease have on the patient's life? Is it contagious, disfiguring, etc.?

Metastatic bone disease is not contagious, nor is it disfiguring.
 
One of the impacts of the disease is that some patients will have metal surgical hardware placed in their body to treat a fracture or a bone about to fracture.

Surgery for Metastatic Bone Disease at the University of Washington

If you are interested in making an appointment to discuss this procedure, you can request an appointment using our online referrals website. To request a referral online, please click here. You can also call 206-598-4288 (outside the Seattle area: 800-440-3280) to make an appointment.


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