Aspirin and Related Drugs (NSAIDs).
Last updated Friday, May 11, 2007
Non-aspirin salicylatesNSAIDs Aspirin, salicylates, and many over the counter pain relievers
belong to a group of drugs called the nonsteroidal anti-inflammatory
drugs (or NSAIDs for short).
Three of the main types of NSAIDs that arthritis patient often use
are acetaminophen, ibuprofen, and analgesic (pain-relieving) rubs. Acetaminophen Acetaminophen is used for relief of headaches, fever, and mild pain.
However, it does not reduce the inflammation that is present in many
forms of arthritis. Some brand names include Tylenol and Datril. You
can substitute it for aspirin or other salicylates to control pain, but
not for the reduction of inflammation. Your doctor will let you know
whether acetaminophen would be useful for you.
Aspirin is often combined with acetaminophen in a single tablet for
relief of arthritis and other painful conditions. Sometimes other drugs
such as caffeine, an antihistamine, nasal drying agents, and sedatives
are also added. Although some of these preparations may have special
uses for certain acute conditions such as a cold or a headache, they
should not be taken for a chronic (long-term) form of arthritis. If a
combination is required, each drug should be prescribed separately. The
dose of each should be adjusted individually to achieve the greatest
benefit with the fewest side effects.
Ibuprofen Ibuprofen is an NSAID that is now available without a prescription for
control of aches, pains, fever, and menstrual cramps. (Some brand-name
examples are Advil and Nuprin.) The benefits of this drug are similar
to those of aspirin, but overdoses are less likely to cause serious
illness than are overdoses of aspirin.Analgesic (pain-relieving) rubs Analgesic (pain-relieving) rubs are liquids or ointments that often
contain some form of salicylate. They are meant to be rubbed onto the
skin over a painful area such as a joint for short-term pain relief.
They produce their effect by creating a sensation of numbness and
warmth in the skin, which may provide some feeling of relief from the
underlying pain. They may also work as counter-irritants that increase
local blood flow and modify the perception of pain.
The salicylates and other substances such as menthol and camphor in
these rubs are not well absorbed. This means that they do not penetrate
the skin and reach underlying painful joints. Only a small amount
actually reaches the circulation to be spread throughout the body.
These rubs do not reduce inflammation.
Analgesic rubs are very toxic if taken internally. They should be kept away from children.
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