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Gout.

Last updated Wednesday, December 22, 2004

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Incidence and risk factors

Incidence

Gout affects more than one million Americans from all walks of life. It can occur at any age, but the first attack often affects men between the ages of 40 and 50.

Gout affects women as well. In fact, the number of postmenopausal women who have gout is increasing. However, it sometimes is difficult to diagnose gout in these women because they also may have osteoarthritis, a disease that causes the breakdown of joint tissue, leading to joint pain and stiffness. Among the affected joints are finger joints, the joint at the base of the thumb, and the joint at the base of the big toe. The confusion occurs because urate (the salt of uric acid) crystals tend to deposit in areas where osteoarthritis already has caused joint damage, such as in the hands and feet.

Lifestyle risk factors

Gout once was mistakenly thought to be a disease of the wealthy because it seemed to be caused by eating rich foods and by drinking too much alcohol. Although diet and excessive drinking do have something to do with gout, they are not the main cause of the disorder.

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