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HomeAbout fibromyalgiaIncidence and risk factorsImportant medical illnesses to considerApproach to the patient with suspected fibromyalgiManagement and treatmentTreatmentStress and distressSleep disturbanceStretching and reactivationOther issuesWhen to refer

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Technical Information: Guidelines for the Diagnosis and Treatment of Fibromyalgia.

Edited By: Gregory C. Gardner, M.D.
Last updated Friday, January 07, 2005

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Management and treatment

Treatment

Treatment consists of three parts; understanding sources of stress that cause the patient distress, address sleep disturbance, and address stretching and reactivation.

There are currently only theories on what causes FMS but most now focus on a central causes such as neuroendocrine abnormalities. Whether biological or psychological or some combination of both, our role as health care providers is to give our patients the best care available to maximize health and quality of life. In a few years it is hoped that these guidelines will be updated to reflect important breakthroughs in the understanding and treatment of FMS.

Stress and distress

It is important to know the patient and how they deal with stress and what sources of stress are present in their lives. Patients may benefit from the care of a pain psychologist or counselor to help sort these issues out. Patients with mood disorders should of course be treated, as few patients with active depression/anxiety will get better without therapy.

Sleep disturbance

Try to understand why the patient feels they don’t sleep well. It may be related to anxiety or depression and if so treatment for these may make a difference. If sleep apnea is possible it should be addressed with a sleep study. Sleep hygiene includes taking time to relax before trying to sleep and avoid vigorous exercise within several hours of initiating sleep. Medication for sleep should be given if the above issues are not identified. Medications are selected for the ability to induce sleep and not disturb stage four sleep. Medication for sleep can include the following:

For mild cases suggest melatonin or low dose diphenylhydramine (Benadryl). Tylenol PM is an easy dosing form for diphenylhydramine.

  • Cyclopenzaprine, a muscle relaxant; begin with 5-10 mg/night and may increase as needed to maximum of 40-50 mg/night.
  • Low dose tricyclic antidepressant i.e. amytriptyline 10-75 mg/night, nortriptyline 10-75 mg/night, trazadone 25-100 mg/night.
  • Effexor has been used for sleep and for chronic pain.
  • Ambien is an expensive medication but can be used if all else fails. Doses of 5-20 mg can be used.
  • Neurontin can help with sleep and has been used for chronic pain as well. Dose of 300 to 1200 mg may be reasonable.

Stretching and reactivation

This is one of the most important aspects of treatment. Aerobic conditioning improves pain control by raising pain thresholds, improves physical stamina, and can even lower anxiety and depression scores. If done progressively, it also helps to restore confidence in the ability to be active. It is useful to send the patient to physical therapy for initiation of the AM stretching program and to help them develop a slowly progressive aerobic program. Occasionally more intense physical therapy program may be helpful to initiate exercise or to treat a flare. Generally though, weeks of physical therapy are not useful treatment should be directed to make patients independent of the medical system. Occasional massage therapy may be useful for some patients. Cognitive behavioral therapy has emerged as a potentially useful form of therapy to address somatic illness. It entails stretching, reactivation, stress management, and non-pharmacological pain management techniques.

Other issues

Opiates should be avoided. Rarely a small bank account of low potency narcotics can be provided i.e. 10 Tylenol #3 with the understanding that these will be refilled only once a month. Tramadol or Ultram can also be used as an alternative. We rarely recommend more than 3 per day. NSAIDs rarely work in FMS and most patients have previously tried them. Patients who feel they need continuous narcotics should be referred to a pain clinic for multidisciplinary care including psychological evaluation. In general, patients with FMS and other somatic pain syndromes feel under-treated with narcotics no matter the dose.

When to refer

Referral to a pain specialist or multidisciplinary pain clinic should be done only after the primary care provider has exhausted efforts on behalf of the patient. Keeping people with FMS in the primary care setting may lessen sense of disability. It is important for the primary care provider to give the person with FMS the majority stake in their own improvement. Stretching, exercising, staying involved in life without overscheduling, and seeking counseling for personal or family issues are to be done by the patient as part of the overall therapy. Goals should be modest i.e. 50-75% improvement but a motivated patient may achieve more than this. DO NOT consider success a return to pre-FMS pain and fatigue levels. If the patient is unable to assume these responsibilities, then a referral to a pain specialist may be warranted to give the patient greater assistance.

Final thought: Sir William Osler taught us that “It is more important to know what sort of patient has a disease than what sort of disease a patient has.” This patient centered focus is very important when trying to help our patients with fibromyalgia.

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Disclaimer

This resource has been provided by the University of Washington Department of Orthopaedics and Sports Medicine as general information only. This information may not apply to a specific patient. Additional information may be found at http://www.orthop.washington.edu or by contacting the UW Department of Orthopaedics and Sports Medicine.


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