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HomeIntroductionBiology of articular cartilagePathophysiology of osteoarthritisClinical aspects of osteoarthritisJoint areas involved in primary osteoarthritisClinical characteristics of osteoarthritisRadiographic featuresBasic differential diagnosisManagement of osteoarthritisExercise and osteoarthritisAssistive devicesMedicationsSurgical therapyConclusion & bibliography

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Continuing Medical Education: Understanding Osteoarthritis.

Edited By: Gregory C. Gardner, M.D.
Last updated Friday, January 07, 2005

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Clinical aspects of osteoarthritis

Joint areas involved in primary osteoarthritis

  • DIPs
  • PIPs
  • 1st CMC
  • Hips
  • Knees
  • 1st MTP
  • Cervical Spine
  • Lumbar Spine

If other areas involved think history of trauma or one of the metabolic causes of OA such as hemachromatosis or CPPD.

Clinical characteristics of osteoarthritis

  • Mild morning stiffness (<15 minutes)
  • Pain with use
  • Swelling (synovial fluid is noninflammatory)
  • Gelling (stiffness after rest)
  • Boney deformity (Heberden's and Bouchard's nodes)

Radiographic features

  • Non-uniform joint space narrowing
  • Subchondral sclerosis
  • Subchondral cysts
  • Osteophytes

Basic differential diagnosis

  • Rheumatoid arthritis
  • Psoriatic arthritis
  • Tophaceous urate gout
  • Calcium pyrophosphate deposition disease

Surgery for arthritis at the University of Washington

If you are interested in making an appointment to discuss this procedure, you can request an appointment using our online referrals website. To request a referral online, please click here. You can also call 206-598-4288 (outside the Seattle area: 800-440-3280) to make an appointment.


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