Oncology Research Lab

Sarcoma is a rare cancer of connective tissue that affects both children and adults in all areas of the body. Education and awareness are critical to early detection and receiving adequate treatment.

The Multidisciplinary Sarcoma Service's orthopaedic team is lead by Drs. Conrad and Davidson and serves patients from across the Pacific Northwest (WAMI region). Research takes advantage of this multidisciplinary approach through Sarcobase, a database, and the Bone and Soft Tissue Tumor Bank with the shared goal of improving quality of life and improving current technique.

Sarcobase

Fit Bits stepwatches

Patients seen at our clinic are invited to participate in this dedicated bone and soft tissue tumor registry. This registry hasbeen maintained for ten years and has over 5,000 entries. This database provides researchers with information about bone and soft tissue tumors and can be used to generate future studies.

Fit Bits stepwatches (shown to the left) will be used as functional outcome components  to Sarcobase to better assess patient mobility before and after surgery.

Bone and Soft Tissue Tumor Bank

We ask patients to participate by donating their tissue collected at a time of surgery to our bone and soft tissue tumor bank. This collected tissue is tissue that pathologists do not need to perform their clinical pathological diagnosis. From our tissue repository, future researchers may approach us and conduct research projects for a specific tumor. This tumor bank has been active for the past ten years and has over 1,000 samples.

Limb Salvage

Comparing surgical techniques, allograft versus implant (cemented/uncemented) reconstructions, perioperative and postoperative complication rates, and functional outcomes in both pediatric and adult populations.

Functional Outcome Measures

We will compare the EQ-5D and SF-6D (among other surveys such as the TESS, SF36, and ASK-p) in patients treated for soft tissue sarcoma. We will also validate the use of a step-counter (pedometer) for the evaluation of physical function following management of bone and soft tissue sarcoma and its comparison with these functional assessment surveys.

Surgical Navigation

Preoperative scans (CT) are uploaded onto the computer system and surgical planning occurs. Intraoperatively the patient and the tumor can be matched with preoperative imaging via Doppler radar to improve tumor orientation intraoperatively (e.g., pelvis, spine), confirm and document tumor margins, and assist with reconstructive metrics.